From laboratory investigation, modafinil has minor to no affinity for serotonin or norepinephrine transporters and does not directly connect with these programs.[sixteen][one hundred forty four] Having said that, scientific studies have revealed that elevated concentrations of norepinephrine and serotonin can occur as an indirect effect subsequent

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In summary, the bulk of study into modafinil’s wake-advertising mechanism has concentrated mostly on probable extracellular things to do of modafinil. We suggest that extra work be completed on inspecting opportunity intracellular mechanisms of modafinil and getting a position of convergence of modafinil’s stimulant and neuroprotective results.